Draft genome sequences of extended-spectrum

Draft genome sequences of extended-spectrum ß-lactamase-producing Enterobacter aerogenes isolated from swine and human

Dr Luria Founou and colleagues, reported on the genome sequences of two Enterobacter aerogenes strains (HN503E2II and PN108E5IIB) isolated from two Cameroonian abattoirs. Using an Illumina MiSeq platform, the researchers de novo assembled the raw reads using CLC Genomics Workbench and SPAdes. The assembled contigs were annotated, and antibiotic resistance genes, virulence factors and plasmids were identified through in silico analyses. The authors revealed that the genome of both isolates harboured several resistance genes associated with resistance to ß-lactams, fluoroquinolones, aminoglycosides, fosfomycin, phenicols, sulphonamides, trimethoprim, macrolides and tetracycline. They concluded that these genomes could provide valuable information in the understanding of genetic structure of Enterobacter aerogenes in Africa.

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